Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis.,European Spine Journal

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Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis.
European Spine Journal ( IF 2.6 ) Pub Date : 2020-02-24 , DOI: 10.1007/s00586-020-06339-1
Rikke Krüger Jensen _{1,

2} , Tue Secher Jensen _{2,

3,

4} , Bart Koes _{1,

5} , Jan Hartvigsen _{1,

2}

Affiliation

Abstract

Purpose

To estimate the prevalence of degenerative lumbar spinal stenosis (LSS) in adults, identified by clinical symptoms and/or radiological criteria.

Methods

Systematic review of the literature. Pooled prevalence estimates by care setting and clinical or radiological diagnostic criteria were calculated and plotted [PROSPERO ID: CRD42018109640].

Results

In total, 41 papers reporting on 55 study samples were included. The overall risk of bias was considered high in two-thirds of the papers. The mean prevalence, based on a clinical diagnosis of LSS in the general population, was 11% (95% CI 4–18%), 25% (95% CI 19–32%) in patients from primary care, 29% (95% CI 22–36%) in patients from secondary care and 39% (95% CI 39–39%) in patients from mixed primary and secondary care. Evaluating the presence of LSS based on radiological diagnosis, the pooled prevalence was 11% (95% CI 5–18%) in the asymptomatic population, 38% (95% CI − 10 to 85%) in the general population, 15% (95% CI 13–18%) in patients from primary care, 32% (95% CI 22–41%) in patients from secondary care and 21% (95% CI 16–26%) in a mixed population from primary and secondary care.

Conclusions

The mean prevalence estimates based on clinical diagnoses vary between 11 and 39%, and the estimates based on radiological diagnoses similarly vary between 11 and 38%. The results are based on studies with high risk of bias, and the pooled prevalence estimates should therefore be interpreted with caution. With an growing elderly population, there is a need for future low risk-of-bias research clarifying clinical and radiological diagnostic criteria of lumbar spinal stenosis.

Graphic abstract

These slides can be retrieved under Electronic Supplementary Material.

中文翻译：

普通和临床人群中腰椎管狭窄的患病率：系统评价和荟萃分析。

摘要

目的

评估通过临床症状和/或放射学标准确定的成年人退行性腰椎管狭窄症（LSS）的患病率。

方法

系统评价文献。计算并绘制由护理机构和临床或放射学诊断标准汇总的患病率估计值[PROSPERO ID：CRD42018109640]。

结果

总共包括41篇报道55个研究样本的论文。在三分之二的论文中，偏见的总体风险很高。根据一般人群对LSS的临床诊断，平均患病率为11％（95％CI 4–18％），25％（95％CI 19–32％）来自初级保健的患者，29％（95二级保健患者的CI百分比为22–36％，初级和二级保健患者的百分比CI为39％（95％CI 39–39％）。根据放射学诊断评估LSS的存在，无症状人群的合并患病率为11％（95％CI 5–18％），普通人群为38％（95％CI − 10至85％），为15％（初级保健和二级保健混合人群中95％CI 13–18％），二级保健患者32％（95％CI 22–41％）和21％（95％CI 16–26％）关心。