Microgravity affects plant growth and content. A three-dimensional clinostat was used at 4 rotations/min to rotate the seeds of Triticum aestivum cultivar (Ammon) in three dimensions for 7 days, following which the antioxidant activities of ethanolic extracts were evaluated using both nitric oxide- and hydrogen peroxide-scavenging activities. The antidiabetic activities of ethanolic extracts were evaluated by measuring the concentration of plasma glucose, insulin, C peptide, and glycated hemoglobin (HbA1c); determining the number of β cells in the pancreatic islets; and performing the glucose tolerance test. Furthermore, the effects of the ethanolic extracts on the lipid profile and liver function were estimated. After rats were sacrificed, their pancreases were isolated and used for histopathological processing. The results indicated that the antioxidant potential and antioxidant metabolite content were significantly increased under microgravity conditions in comparison to those under normal gravity conditions. Rats treated with an extract of wheatgrass (T. aestivum) germinated over a period of 6–10 days under microgravity (WGM) showed a significant reduction in the levels of serum glucose, HbA1C, urea, creatinine, aspartate aminotransferase and alanine aminotransferase, and insulin resistance compared to rats treated with an extract of wheatgrass germinated under gravity. Additionally, the total cholesterol and low-density lipoprotein cholesterol levels were significantly decreased. In contrast, high-density lipoprotein cholesterol, C-peptide, and insulin levels rose significantly after treatment with T. aestivum germinated under microgravity. WGM is a promising potential diabetic treatment without side effects with a low manufacturing cost.

微重力影响植物的生长和含量。使用三维回转器以 4 转/分钟的速度将小麦品种 (Ammon) 的种子进行三维旋转 7 天，然后使用一氧化氮和过氧化氢清除来评估乙醇提取物的抗氧化活性活动。通过测量血浆葡萄糖、胰岛素、C肽和糖化血红蛋白（HbA1c）的浓度来评估乙醇提取物的抗糖尿病活性；确定胰岛中 β 细胞的数量；并进行葡萄糖耐量测试。此外，还评估了乙醇提取物对血脂和肝功能的影响。处死大鼠后，分离其胰腺并用于组织病理学处理。结果表明，与正常重力条件下相比，微重力条件下的抗氧化潜力和抗氧化代谢物含量显着增加。在微重力 (WGM) 下，用小麦草 ( T. aestivum ) 提取物处理发芽 6-10 天的大鼠，其血糖、HbA1C、尿素、肌酐、天冬氨酸转氨酶和丙氨酸转氨酶水平显着降低，并且与用重力下发芽的小麦草提取物治疗的大鼠相比，胰岛素抵抗。此外，总胆固醇和低密度脂蛋白胆固醇水平显着降低。相比之下，在微重力下发芽的普通小麦处理后，高密度脂蛋白胆固醇、C 肽和胰岛素水平显着上升。 WGM 是一种有前景的潜在糖尿病治疗方法，无副作用且制造成本低。