Rh(III)-Catalyzed Denitrogenative [4+2] Annulation of Benzamides and 3-Diazoindolin-2-imines: Expedient Access to Indolo[2,3-c] isoquinolin-5-ones.,Chemistry - An Asian Journal

当前位置： X-MOL 学术 › Chem. Asian J. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Rh(III)-Catalyzed Denitrogenative [4+2] Annulation of Benzamides and 3-Diazoindolin-2-imines: Expedient Access to Indolo[2,3-c] isoquinolin-5-ones.
Chemistry - An Asian Journal ( IF 3.5 ) Pub Date : 2020-02-22 , DOI: 10.1002/asia.202000096
Kuntal Pal ₁ , Souvik Adak ₁ , Arnab Dey ₁ , Chandra M R Volla ₁

Affiliation

An effective and pragmatic strategy for the synthesis of structurally diverse indolo[2,3- c ]isoquinolin-5-ones has been developed via a Rh(III)-catalyzed C-H activation and [4+2] annulation reaction of N -methoxybenzamides and 3-diazoindolin-2-imines. The reaction involves the efficient formation of two new (one C-C and one C-N) bonds under operationally simple conditions and has the benefits of a broad substrate scope.

中文翻译：

Rh（III）催化的苯甲酰胺和3-Diazoindolin-2-imines的脱氮[4 + 2]环化反应：便捷使用Indolo [2,3-c] isoquinolin-5-ones。

通过Rh（III）催化的CH活化和N-甲氧基苯甲酰胺的[4 + 2]环化反应，已开发出一种有效而实用的合成结构多样的吲哚[2,3-c]异喹啉-5-酮的策略。 3-重氮吲哚-2-亚胺。该反应涉及在操作简单的条件下有效形成两个新的（一个CC和一个CN）键，并具有广泛的底物范围的优点。

更新日期：2020-03-12

点击分享查看原文

点击收藏

阅读更多本刊最新论文