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Oxidized protein aggregates: Formation and biological effects.
Free Radical Biology and Medicine ( IF 7.1 ) Pub Date : 2020-02-22 , DOI: 10.1016/j.freeradbiomed.2020.02.014
Tilman Grune 1
Affiliation  

The study of protein aggregates has a long history. While in the first decades until the 80ies of the 20th century only the observation of the presence of such aggregates was reported, later the biochemistry of the formation and the biological effects of theses aggregates were described. This review focusses on the complexity of the biological effects of protein aggregates and its potential role in the aging process.

中文翻译:

氧化的蛋白质聚集体:形成和生物学效应。

蛋白质聚集体的研究历史悠久。虽然直到20世纪80年代的头几十年,仅报道了这种聚集体的存在,但后来描述了这些聚集体的形成生物化学和生物学效应。这篇综述着重于蛋白质聚集体生物学效应的复杂性及其在衰老过程中的潜在作用。
更新日期:2020-02-23
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