Steroidal saponins are a group of glycosides widely distributed among monocotyledonous families. They exert a wide spectrum of biological effects including cytotoxic and antitumor properties which are the most studied. This review is an update of our previous paper—Saponins as cytotoxic agents (Podolak et al. in Phytochem Rev 9:425–474, 2010) and covers studies that were since published (2010–2018). In this paper we refer to steroidal saponins presenting results of cytotoxicity studies, mechanisms of action and structure–activity relationships.

中文翻译：

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皂苷作为细胞毒性剂：最新动态（2010-2018年）。第一部分-类固醇皂苷

甾体皂苷是一组在单子叶植物家族中广泛分布的糖苷。他们发挥了广泛的生物学效应，包括细胞毒性和抗肿瘤特性，这是研究最多的。这篇综述是对我们之前的论文《皂苷作为细胞毒性剂》的更新（Podolak等人，Phytochem Rev 9：425–474，2010），涵盖了自2010年至2018年发表的研究。在本文中，我们指的是甾体皂苷，其表现出细胞毒性研究的结果，作用机理以及构效关系。