Optimising gene editing for cancer therapy.,Nature Cell Biology

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Optimising gene editing for cancer therapy.
Nature Cell Biology ( IF 17.3 ) Pub Date : 2020-02-21 , DOI: 10.1038/s41556-020-0480-5
Katie Troike _{1,

2} , Justin D Lathia _{1,

2,

3,

4}

Affiliation

Gene editing holds promise for the treatment of cancers that are driven by well-characterised molecular alterations. A study now provides a proof of concept for the feasibility of in vivo gene editing to correct TERT mutations in glioblastoma, providing a platform for the direct manipulation of genetic alterations to reduce tumour growth.

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