Preprocessing, analysis and quantification in single‐voxel magnetic resonance spectroscopy: experts' consensus recommendations,NMR in Biomedicine

当前位置： X-MOL 学术 › NMR Biomed. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Preprocessing, analysis and quantification in single‐voxel magnetic resonance spectroscopy: experts' consensus recommendations
NMR in Biomedicine ( IF 2.7 ) Pub Date : 2020-02-21 , DOI: 10.1002/nbm.4257
Jamie Near _{1,

2} , Ashley D Harris _{3,

4,

5} , Christoph Juchem ₆ , Roland Kreis ₇ , Małgorzata Marjańska ₈ , Gülin Öz ₈ , Johannes Slotboom ₉ , Martin Wilson ₁₀ , Charles Gasparovic ₁₁

Affiliation

Douglas Mental Health University Institute and Department of Psychiatry, McGill University, Montreal, Canada.
McConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, Canada.
Department of Radiology, University of Calgary, Calgary, Canada.
Alberta Children's Hospital Research Institute, Calgary, Canada.
Hotchkiss Brain Institute, Calgary, Canada.
Departments of Biomedical Engineering and Radiology, Columbia University, New York, New York.
Departments of Radiology and Biomedical Research, University Bern, Switzerland.
Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota.
Support Center for Advanced Neuroimaging (SCAN), Neuroradiology, University Hospital Inselspital, Bern, Switzerland.
Centre for Human Brain Health and School of Psychology, University of Birmingham, Birmingham, UK.
The Mind Research Network, Albuquerque, New, Mexico.

Once an MRS dataset has been acquired, several important steps must be taken to obtain the desired metabolite concentration measures. First, the data must be preprocessed to prepare them for analysis. Next, the intensity of the metabolite signal(s) of interest must be estimated. Finally, the measured metabolite signal intensities must be converted into scaled concentration units employing a quantitative reference signal to allow meaningful interpretation. In this paper, we review these three main steps in the post‐acquisition workflow of a single‐voxel MRS experiment (preprocessing, analysis and quantification) and provide recommendations for best practices at each step.

中文翻译：

单体素磁共振波谱的预处理、分析和定量：专家共识建议

获取 MRS 数据集后，必须采取几个重要步骤来获得所需的代谢物浓度测量值。首先，必须对数据进行预处理，为分析做好准备。接下来，必须估计感兴趣的代谢物信号的强度。最后，必须使用定量参考信号将测得的代谢物信号强度转换为比例浓度单位，以便进行有意义的解释。在本文中，我们回顾了单体素 MRS 实验的采集后工作流程中的这三个主要步骤（预处理、分析和量化），并为每个步骤的最佳实践提供了建议。

更新日期：2020-02-21

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11