Cationic adduction causes poor sensitivity and increases spectral complexity during mass spectral analysis of oligonucleotides and alkylamines are used to reduce this adduction. It is unclear the effect of the physiochemical properties of the alkylamines on the reduction of the cationic adduction.

中文翻译：

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使用电喷雾解吸电离模拟寡核苷酸的阳离子加成

在寡核苷酸的质谱分析过程中，阳离子加成反应会导致灵敏度降低，并增加光谱复杂性，而烷基胺可减少这种加成反应。尚不清楚烷基胺的物理化学性质对减少阳离子加合物的影响。