Electrochemical Determination of the Effect of Caffeic Acid onto the Interaction between Idarubicin and DNA by Single‐use Disposable Electrodes,Electroanalysis

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Electrochemical Determination of the Effect of Caffeic Acid onto the Interaction between Idarubicin and DNA by Single‐use Disposable Electrodes
Electroanalysis ( IF 2.7 ) Pub Date : 2020-02-21 , DOI: 10.1002/elan.201900722
Baha Öndeş ₁ , Mihrican Muti ₁

Affiliation

Now it is well known, antioxidant may affect the interaction of anticancer drugs and DNA. This study aims to investigate the interaction between Idarubicin and DNA and the effect of caffeic acid on this interaction. Disposable, inexpensive, easy handle electrodes were used in this study to investigate the interaction of idarubicin and DNA electrochemically. Idarubicin (IDR) is an anthracyline antitumor antibiotic, which used against one or more types of leukemia.

中文翻译：

一次性使用电极电化学测定咖啡酸对伊达比星与DNA相互作用的影响

现在众所周知，抗氧化剂可能会影响抗癌药物与DNA的相互作用。这项研究旨在调查依达比星与DNA之间的相互作用以及咖啡酸对此相互作用的影响。一次性，便宜，易于操作的电极被用于这项研究中以电化学方式研究伊达比星和DNA的相互作用。依达比星（IDR）是一种蒽环类抗肿瘤抗生素，用于抗一种或多种类型的白血病。

更新日期：2020-02-21

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