Journal of Proteomics ( IF 2.8 ) Pub Date : 2020-02-21 , DOI: 10.1016/j.jprot.2020.103719 D A Moreno-Pérez 1 , M A Patarroyo 2
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Deciphering Plasmodium vivax biology has long been a challenge for groups working on this parasite, mainly due to the complications involved in propagating it in vitro. However, adapting P. vivax strains in non-human primates and the arrival of high-performance analysis methods has led to increased knowledge regarding parasite protein composition and the ability of some molecules to trigger an immune response or participate in protein-protein interactions. This review describes the state of the art concerning proteomics-, immunomics- and interatomics-related P. vivax omic studies, discussing their potential use in developing disease control methods.
中文翻译：
使用组学数据推断间日疟原虫蛋白质生物学
长期以来，对间日疟原虫的生物学进行解密一直是研究该寄生虫的挑战，这主要是由于在体外传播该病的复杂性。但是，在非人类灵长类动物中适应间日疟原虫菌株以及高性能分析方法的到来，导致人们对寄生虫蛋白质组成以及某些分子触发免疫反应或参与蛋白质-蛋白质相互作用的能力的了解增加。这篇综述描述了与蛋白质组学，免疫组学和原子间相关的间日疟原虫组学研究的最新发展，并讨论了它们在开发疾病控制方法中的潜在用途。
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