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Same Concept Different Outcomes: Sugars Determine Circadian Clock Protein Fate in Animals and Plants.
Molecular Plant ( IF 17.1 ) Pub Date : 2020-02-21 , DOI: 10.1016/j.molp.2020.02.013
Wei Liu 1 , Joshua M Gendron 1
Affiliation  

The circadian clocks of plants and animals are recruiting similar cellular systems to regulate PTMs of circadian clock proteins, but distinctions remain. Circadian clocks in both autotrophic and heterotrophic organisms can be refined by PTM cascades, but the same PTMs can have different functional outcomes. The role of protein glycosylation is a clear example of this dichotomy, where circadian clock transcription factors in plants and animals are modified by sugars but this results in opposite effects on protein stability.



中文翻译:

相同概念的不同结果:糖决定动植物的昼夜节律蛋白质命运。

植物和动物的生物钟正在募集类似的细胞系统来调节生物钟蛋白的PTM,但仍存在区别。自养生物和异养生物的昼夜节律时钟可以通过PTM级联完善,但相同的PTM可以具有不同的功能结果。蛋白质糖基化的作用是这种二分法的一个明显例子,其中动植物的昼夜节律转录因子被糖修饰,但这对蛋白质稳定性产生相反的影响。

更新日期:2020-02-21
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