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Neonatal morbidity and small and large size for gestation: a comparison of birthweight centiles.
Journal of Perinatology ( IF 2.4 ) Pub Date : 2020-02-20 , DOI: 10.1038/s41372-020-0631-3
Robert D Cartwright 1 , Ngaire H Anderson 2, 3 , Lynn C Sadler 3, 4, 5 , Jane E Harding 1 , Lesley M E McCowan 3, 4 , Christopher J D McKinlay 1, 6, 7
Affiliation  

OBJECTIVE To compare rates of small- and large-for-gestational age (SGA and LGA) neonates using four different weight centiles, and to relate these classifications to neonatal morbidity. STUDY DESIGN Neonates born at 33-40 weeks' gestation in a multiethnic population were classified as SGA or LGA by population reference (Fenton), population standard (INTERGROWTH), fetal growth curves (WHO), and customized (GROW) centiles. Likelihood of composite morbidity was determined compared with a common appropriate-for-gestational age referent group. RESULT Among 45,505 neonates, SGA and LGA rates varied up to threefold by different centiles. Those most likely to develop neonatal morbidity were SGA or LGA on both the population reference and an alternative centile. Customized centiles identified over twice as many at-risk SGA neonates. CONCLUSIONS Customized centiles were most useful in identifying neonates at increased risk of morbidity, and those that were small on both customized and population reference centiles were at the highest risk.

中文翻译:

新生儿发病率和妊娠大小:出生体重百分位数的比较。

目的 使用四种不同的体重百分位数来比较小胎龄和大胎龄儿(SGA 和 LGA)新生儿的比率,并将这些分类与新生儿发病率联系起来。研究设计 在多民族人群中出生于 33-40 周妊娠的新生儿通过人群参考 (Fenton)、人群标准 (INTERGROWTH)、胎儿生长曲线 (WHO) 和定制 (GROW) 百分位数被分类为 SGA 或 LGA。与常见的适合孕龄参考组相比,确定了复合发病率的可能性。结果 在 45,505 名新生儿中,SGA 和 LGA 率因百分位数不同而变化高达三倍。那些最有可能发展为新生儿发病率的是人口参考和替代百分位上的 SGA 或 LGA。定制的百分位数确定了两倍以上的高危 SGA 新生儿。
更新日期:2020-02-20
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