当前位置: X-MOL 学术Clin. Gastroenterol. Hepatol. › 论文详情
Differences in Incidence and Mortality Trends of Colorectal Cancer, Worldwide, Based on Sex, Age, and Anatomic Location.
Clinical Gastroenterology and Hepatology ( IF 7.958 ) Pub Date : 2020-02-20 , DOI: 10.1016/j.cgh.2020.02.026
Martin Cs Wong,Junjie Huang,Veeleah Lok,Jingxuan Wang,Franklin Fung,Hanyue Ding,Zhi-Jie Zheng

BACKGROUND & AIMS We studied incidence and mortality trends of colorectal cancer (CRC) in 39 countries according to age, sex, and anatomical location (colon vs rectum). METHODS We retrieved incidence data from registries from 36 countries. The registries included: Cancer Incidence in 5 Continents (CI5) volumes I-XI; the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute; and the Nordic Cancer Registries from Europe. We obtained mortality data from 39 countries of the World Health Organization database. We evaluated average annual percent changes in CRC incidence and mortality in the past decade using joinpoint regression analysis. RESULTS From 2007 to 2016, 2006 to 2015, or 2005 to 2014, depending on the availability of the data, the incidence of colon cancer increased in 10 of 36 countries analyzed (all in Asia or Europe); India had the greatest increase, followed by Poland. All 10 of these countries have medium-high Human Development Index (HDI) scores. Six countries had a decrease in colon cancer incidence; these countries had the highest HDI scores; the United States (US) had the greatest decrease, followed by Israel. Seven countries (including all countries from Northern America) had a decrease in incidence among persons older than 50 y. Eight countries had an increase in colon cancer incidence among persons younger than 50 y, including the United Kingdom and India. Countries with a decreased or stable incidence among persons 50 y or older but a significant increase in persons younger than 50 y included Germany, Australia, the US, Sweden, Canada, and the United Kingdom. Only Italy had a decrease in CRC incidence among persons younger than 50 y. Among women, 12 of 36 countries (all from Asia and Europe) had an increase in colon cancer incidence and 7 countries had a decrease; India had the greatest increase followed by Slovenia. Five of 36 countries had an increase in incidence of rectal cancer and 8 countries had a decrease; Ecuador and Thailand had the greatest increases in incidence. The incidence of rectal cancer among persons younger than 50 y increased significantly in Finland, Australia, Canada, the US, and Netherlands. Four countries had an increase in incidence of rectal cancer in women; Ecuador had the greatest increase followed by Thailand. Incidence of rectal cancer in women decreased in 8 countries. Among women younger than 50 y, rectal cancer incidence increased, despite a decrease in women older than 50 y, in Costa Rica, Slovenia, Japan, Slovakia, Canada and the US had an increase in incidence although their elder population had a stable or decreased incidence. Twenty-four countries reported a reduction in CRC mortality, including the North America, Oceania, and most European countries. Nevertheless, some countries from Asia, Latin America, and Southern Europe had significant increases in CRC mortality. CONCLUSIONS In an analysis of incidence and mortality databases from 39 countries, we found that the incidence of colon and rectal cancers has continued to increase in countries with medium-high HDI and in younger populations. Preventive strategies are needed for countries with increasing CRC and rectal cancer incidence and mortality.
更新日期:2020-02-21

 

全部期刊列表>>
宅家赢大奖
向世界展示您的会议墙报和演示文稿
全球疫情及响应:BMC Medicine专题征稿
新版X-MOL期刊搜索和高级搜索功能介绍
化学材料学全球高引用
ACS材料视界
x-mol收录
自然科研论文编辑服务
南方科技大学
南方科技大学
西湖大学
中国科学院长春应化所于聪-4-8
复旦大学
课题组网站
X-MOL
深圳大学二维材料实验室张晗
中山大学化学工程与技术学院
试剂库存
天合科研
down
wechat
bug