Cardiopulmonary exercise testing (CPET) is viewed by many as the gold standard for assessing exercise capacity in CF, being recommended on an annual basis. However, not all patients undergo CPET for varying reasons. This service evaluation retrospectively reviewed data from 179 (92 male) patients in a single CF centre in the UK to identify such reasons. A total of 75/179 patients underwent CPET, whilst 104/179 did not. Of these 104, 41 patients were ≤ 11 years of age. Of the remaining 63 patients, 26 did not undergo CPET for clinical reasons including needing IV antibiotics, musculoskeletal issues and obesity. Seventeen refused to undergo CPET because of reasons such as an unwillingness to travel and dislike of CPET. Twenty did not undergo CPET for miscellaneous reasons including difficulty contacting patients. Individuals with FEV₁ < 40%_predicted were 85.7% less likely to undertake a CPET than individuals with FEV₁ ≥ 70%_predicted. Understanding these challenges will assist clinical teams with future implementation of CPET into routine care, by identifying areas for improvement and establishing strategies for enhancing future provision of the test.

中文翻译：

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在囊性纤维化临床实践中实施常规心肺运动测试的挑战：单中心评价

许多人将心肺运动测试（CPET）视为评估CF运动能力的金标准，并建议每年进行一次。但是，并非所有患者都因各种原因接受CPET。这项服务评估回顾性地回顾了英国一个CF中心的179名（92名男性）患者的数据，以找出此类原因。共有75/179例患者接受了CPET，而104/179例则没有。在这104名患者中，有41名患者≤11岁。在其余的63名患者中，有26名由于临床原因未进行CPET，包括需要静脉使用抗生素，肌肉骨骼疾病和肥胖症。由于不愿旅行和不喜欢CPET的原因，有十七名拒绝接受CPET。由于其他原因（包括难以联系患者），二十人没有接受CPET。有FEV的人₁  <40％_预测分别为85.7％不太可能承接CPET不是个人与FEV ₁  ≥70％_的预测。了解这些挑战将帮助临床团队通过确定有待改进的领域并制定加强未来测试的策略，从而将CPET应用于将来的常规护理。