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Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial.
Cardiovascular Research ( IF 10.2 ) Pub Date : 2020-02-17 , DOI: 10.1093/cvr/cvz345 David Corcoran 1, 2 , Aleksandra Radjenovic 1 , Ify R Mordi 1, 2 , Sheraz A Nazir 3 , Simon J Wilson 4 , Markus Hinder 5 , Denise P Yates 6 , Surendra Machineni 7 , Jose Alcantara 5 , Margaret F Prescott 8 , Barbara Gugliotta 5 , Yinuo Pang 6 , Niko Tzemos 9 , Scott I Semple 4 , David E Newby 4 , Gerry P McCann 3 , Iain Squire 3 , Colin Berry 1, 2
Cardiovascular Research ( IF 10.2 ) Pub Date : 2020-02-17 , DOI: 10.1093/cvr/cvz345 David Corcoran 1, 2 , Aleksandra Radjenovic 1 , Ify R Mordi 1, 2 , Sheraz A Nazir 3 , Simon J Wilson 4 , Markus Hinder 5 , Denise P Yates 6 , Surendra Machineni 7 , Jose Alcantara 5 , Margaret F Prescott 8 , Barbara Gugliotta 5 , Yinuo Pang 6 , Niko Tzemos 9 , Scott I Semple 4 , David E Newby 4 , Gerry P McCann 3 , Iain Squire 3 , Colin Berry 1, 2
Affiliation
The effects of serelaxin, a recombinant form of human relaxin-2 peptide, on vascular function in the coronary microvascular and systemic macrovascular circulation remain largely unknown. This mechanistic, clinical study assessed the effects of serelaxin on myocardial perfusion, aortic stiffness, and safety in patients with stable coronary artery disease (CAD).
中文翻译：
Serelaxin 对稳定型冠状动脉疾病患者的血管作用：一项随机安慰剂对照试验。
Serelaxin（一种重组形式的人松弛素 2 肽）对冠状动脉微血管和全身大血管循环中血管功能的影响仍然很大程度上未知。这项机制临床研究评估了 serelaxin 对稳定型冠状动脉疾病 (CAD) 患者心肌灌注、主动脉僵硬度和安全性的影响。
更新日期：2020-02-17
中文翻译：
Serelaxin 对稳定型冠状动脉疾病患者的血管作用：一项随机安慰剂对照试验。
Serelaxin（一种重组形式的人松弛素 2 肽）对冠状动脉微血管和全身大血管循环中血管功能的影响仍然很大程度上未知。这项机制临床研究评估了 serelaxin 对稳定型冠状动脉疾病 (CAD) 患者心肌灌注、主动脉僵硬度和安全性的影响。
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