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Is cannabidiol a scheduled controlled substance? Origin makes the difference.
Drug Discovery Today ( IF 6.5 ) Pub Date : 2020-02-13 , DOI: 10.1016/j.drudis.2020.02.001
Cinzia Citti 1 , Pasquale Linciano 2 , Giuseppe Cannazza 3
Affiliation  

Cannabidiol (CBD) is the main cannabinoid naturally occurring in hemp. It has recently attracted the attention of the scientific community because of its numerous pharmacological activities. However, its legal status changes depending on whether it is chemically synthesized or extracted from the plant: extracted CBD is a scheduled controlled substance, whereas synthetic CBD is not under control. In Europe, extracted CBD is excluded from the cosmetic ingredients of the CosIng database. Given the confusion surrounding these different forms of CBD, there is an urgent need for clarity to shed light from both a regulatory and a chemical point of view. The impurity profiles of synthetic and natural CBD are different and could currently represent the only means to distinguish the origin of this substance.

中文翻译:

大麻二酚是否是预定的受控物质?产地有所作为。

大麻二酚(CBD)是天然存在于大麻中的主要大麻素。由于其众多的药理活性,它最近引起了科学界的关注。但是,其法律地位取决于它是化学合成的还是从植物中提取的:提取的CBD是一种预定的受控物质,而合成CBD不受控制。在欧洲,提取的CBD被排除在CosIng数据库的化妆品成分中。考虑到围绕这些不同形式的CBD的困惑,迫切需要从监管和化学的角度阐明观点。合成和天然CBD的杂质分布不同,目前可能是区分该物质来源的唯一手段。
更新日期:2020-02-13
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