When children require hospital admission, many receive medications with nephrotoxic potential. As such, this can translate into an increased risk of acute kidney injury. In this context, acute kidney injury is hospital acquired, often iatrogenic, and portends risk of adverse outcomes. The Nephrotoxic Injury Negated by Just-in-Time Action study implemented a multicenter hospital-wide quality improvement initiative to detect and reduce nephrotoxin exposure in children aimed at decreasing the rates of potentially avoidable acute kidney injury. This commentary explores the findings and implications of the Nephrotoxic Injury Negated by Just-in-Time Action study.

中文翻译：

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丛林中的危险：明智的护理可减少住院儿童可避免的急性肾脏损伤。

当孩子需要住院时，许多人会接受具有肾毒性潜力的药物。因此，这可能导致急性肾损伤的风险增加。在这种情况下，急性肾脏损伤是医院获得性的，通常是医源性的，预示着不良后果的风险。“及时行动”所否定的肾毒性伤害研究实施了一项跨医院的多中心质量改进计划，以检测和减少儿童的肾毒素暴露，旨在降低可能避免的急性肾损伤的发生率。这篇评论探讨了及时行动研究否定的肾毒性伤害的发现和意义。