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A Calreticulin Tail: C-terminal Mutants of Calreticulin Allow Cancer Cells to Evade Phagocytosis.
Molecular Cell ( IF 14.5 ) Pub Date : 2020-02-20 , DOI: 10.1016/j.molcel.2020.01.024
Amanpreet Kaur 1 , Malini Raghavan 1
Affiliation  

In the current issue of Molecular Cell, Liu et al. (2020) show that the secretion of cancer-linked forms of mutant calreticulin allow cancer cells to escape protective immune responses induced by chemotherapeutic and immunotherapeutic drugs, thereby promoting tumor growth.

中文翻译:


钙网蛋白尾巴:钙网蛋白 C 端突变体允许癌细胞逃避吞噬作用。



在最新一期的《分子细胞》中,刘等人。 (2020) 表明,与癌症相关的突变型钙网蛋白的分泌使癌细胞能够逃避化疗和免疫治疗药物诱导的保护性免疫反应,从而促进肿瘤生长。
更新日期:2020-02-20
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