BACKGROUND To summarise the clinical features of Sclerosing angiomatoid nodular transformation (SANT) of the spleen and to compare the efficacy of three different surgical treatments. METHODS We performed a retrospective analysis of patients with SANT of spleen treated at our center from 2009 to 2018. We compared the efficacy and safety of three different types of surgical procedures. ANOVA and the chi-square test were used for statistical analysis. RESULTS A total of 37 patients were included. Most (35/37; 94.6%) were asymptomatic. A number presented as obscure boundary lesions such that malignancy could not be excluded. Open splenectomy was performed for 12 patients, laparoscopic splenectomy for 12 patients and laparoscopic partial splenectomy for 13 patients. Operation time (P = 0.355), blood loss (P = 0.135), length of hospital stay after operation (P = 0.271) and postoperative complications (P = 0.502) were comparable between the three groups. Duration of drainage tube placement was significantly longer in laparoscopic partial splenectomy patients (P = 0.006). Peak platelet count after operation was significantly lower in laparoscopic partial splenectomy patients (P < 0.001). CONCLUSION Laparoscopic partial splenectomy appears to be a technically feasible and therapeutically effective approach for SANT.

中文翻译：

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脾脏硬化性血管瘤样结节性转化的治疗选择。

背景 总结脾脏硬化性血管瘤样结节性转化（SANT）的临床特征并比较三种不同手术治疗的疗效。方法 我们对 2009 年至 2018 年在我中心治疗的脾脏 SANT 患者进行了回顾性分析。我们比较了三种不同类型外科手术的疗效和安全性。ANOVA和卡方检验用于统计分析。结果共纳入37例患者。大多数（35/37；94.6%）无症状。一些表现为边界不清的病变，因此不能排除恶性肿瘤。开腹脾切除术12例，腹腔镜脾切除术12例，腹腔镜脾部分切除术13例。手术时间（P = 0.355），失血量（P = 0.135），三组术后住院时间（P = 0.271）和术后并发症（P = 0.502）具有可比性。腹腔镜脾部分切除术患者的引流管放置时间显着延长（P = 0.006）。腹腔镜脾部分切除术患者术后峰值血小板计数显着降低（P < 0.001）。结论 腹腔镜脾部分切除术似乎是一种技术上可行且治疗有效的 SANT 方法。