In Situ Electrospinning Wound Healing Films Composed of Zein and Clove Essential Oil,Macromolecular Materials and Engineering

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In Situ Electrospinning Wound Healing Films Composed of Zein and Clove Essential Oil
Macromolecular Materials and Engineering ( IF 4.2 ) Pub Date : 2020-02-20 , DOI: 10.1002/mame.201900790
Mei Qin ₁ , Xiao‐Ju Mou ₁ , Wen‐Hao Dong ₁ , Jia‐Xu Liu ₁ , Hao Liu ₁ , Zhang Dai ₁ , Xiao‐Wei Huang ₁ , Na Wang ₁ , Xu Yan ₂

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Electrospun fibrous membranes have the potential to be effective wound dressings for promoting wound healing. However, the fabrication and application of the common electrospun fibrous wound dressings are usually complicated and separated. Here, electrospun zein/clove essential oil (CEO) fibrous membranes are fabricated and applied as a potential wound dressing through in situ electrospinning process by a portable electrospinning device. The in situ electrospinning process can directly electrospin zein/CEO membranes onto a wound site to cover the wound well and improve the convenience and comfort in use. The as‐spun zein/CEO membranes show a porous structure and exhibit higher gas permeability at 168.2 ± 43.3 mm s⁻¹, with superhydrophilicity to absorb the wound exudate and good biocompatibility as well as antibacterial effects to protect from infection. Moreover, the mice wound model study suggests that in situ electrospun zein/CEO promotes the wound healing process.

中文翻译：

玉米蛋白和丁香精油组成的原位静电纺丝伤口愈合膜

电纺纤维膜具有成为促进伤口愈合的有效伤口敷料的潜力。然而，普通的电纺纤维伤口敷料的制造和应用通常是复杂且分开的。在此，通过便携式静电纺丝设备通过原位静电纺丝工艺来制造静电纺玉米蛋白/丁香精油（CEO）纤维膜，并将其用作潜在的伤口敷料。原位静电纺丝工艺可以将玉米蛋白/ CEO膜直接静电纺到伤口部位，以很好地覆盖伤口，并提高使用的便利性和舒适性。初生玉米蛋白/ CEO膜表现出多孔结构，在168.2±43.3 mm s ^-1时显示出更高的透气性具有超亲水性，可吸收伤口渗出液，具有良好的生物相容性，并具有抗菌作用，可防止感染。此外，小鼠伤口模型研究表明，原位电纺玉米醇溶蛋白/ CEO可促进伤口愈合过程。

更新日期：2020-03-12

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