AIM This study aimed to systematically review the prevalence of diagnosed sleep disorders in people with diabetes and to determine the association between sleep disorders and blood glucose levels and diabetes outcomes. METHODS We conducted a literature search in the following databases: MEDLINE (Pubmed), EMBASE, CINAHL, PsychInfo and Web of Science Citation Index. Meta-analysis (random-effects models) was conducted to estimate the prevalence of sleep disorders in people with diabetes. RESULTS Forty-one articles measured the prevalence of sleep disorders in adults with diabetes. The estimated pooled prevalence of sleep disorders in diabetes was estimated to be 52% (95% CI 42-63%). The highest pooled prevalence was observed for unspecified sleep apnea (69%; 95% CI: 59-78%), followed by obstructive sleep apnea (60%; 95% CI 39-80%), and restless leg syndrome (27%; 95% CI 20-34%). Eleven studies examined the association between sleep disorders and diabetes control and complications. The presence of comorbid sleep disorders was associated with increased diabetes outcomes. CONCLUSIONS Diagnosed sleep disorders are highly prevalent in people with diabetes. Sleep disorders are associated with diabetes outcomes, though there was considerable heterogeneity across studies.

中文翻译：

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睡眠与糖尿病结局之间的关联-系统评价。

目的本研究旨在系统地评估糖尿病患者中诊断出的睡眠障碍的患病率，并确定睡眠障碍与血糖水平和糖尿病预后之间的关联。方法我们在以下数据库中进行了文献检索：MEDLINE（公开），EMBASE，CINAHL，PsychInfo和Web of Science Citation Index。进行荟萃分析（随机效应模型）以评估糖尿病患者睡眠障碍的患病率。结果有41篇文章测量了成年人糖尿病患者睡眠障碍的患病率。糖尿病中睡眠障碍的合并患病率估计为52％（95％CI 42-63％）。未明确的睡眠呼吸暂停合并患病率最高（69％； 95％CI：59-78％），其次是阻塞性睡眠呼吸暂停（60％； 95％CI 39-80％），腿不安综合征（27％; 95％CI 20-34％）。十一项研究检查了睡眠障碍与糖尿病控制和并发症之间的关系。共病睡眠障碍的存在与糖尿病预后的增加有关。结论经诊断的睡眠障碍在糖尿病患者中非常普遍。睡眠障碍与糖尿病结局有关，尽管各研究之间存在相当大的异质性。