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Cholelithiasis in patients treated with Glucagon-Like Peptide-1 Receptor: An updated meta-analysis of randomized controlled trials.
Diabetes Research and Clinical Practice ( IF 6.1 ) Pub Date : 2020-02-19 , DOI: 10.1016/j.diabres.2020.108087
Besmir Nreu 1 , Ilaria Dicembrini 1 , Federico Tinti 1 , Edoardo Mannucci 1 , Matteo Monami 1
Affiliation  

Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) has been associated with cholelithiasis in a previous meta-analysis. The publication of new trials suggests the need for an update. We collected trials with GLP1-RA vs. other therapies, calculating Mantel-Haenszel odds ratio (MH-OR, 95%CI). GLP1-RA significantly increased the risk of cholelithiasis (MH-OR 1.28 [1.11, 1.48]).

中文翻译:

胰高血糖素样肽1受体治疗的患者的胆石症:随机对照试验的最新meta分析。

在先前的荟萃分析中,胰高血糖素样肽1受体激动剂(GLP1-RA)与胆石症相关。新试验的发布表明需要进行更新。我们收集了GLP1-RA与其他疗法的试验,计算出Mantel-Haenszel比值比(MH-OR,95%CI)。GLP1-RA显着增加了胆石症的风险(MH-OR 1.28 [1.11,1.48])。
更新日期:2020-02-20
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