Drosophila neural progenitors require the transcriptional repressor Prospero to promptly establish the neuronal fate of their daughter cells to avoid tumorigenesis. In this issue of Developmental Cell, Liu et al. (2020) find that Prospero is mitotically implanted and forms liquid-like droplets mediating HP1a condensation to permanently repress its targets.

中文翻译：

---

Prospero相分离神经元分化的方式。

果蝇神经祖细胞需要转录抑制子Prospero来迅速建立其子代细胞的神经元命运，从而避免肿瘤的发生。在本期《发育细胞》中，Liu等人。（2020年）发现Prospero被有丝分裂地植入并形成液体状液滴，介导HP1a凝结以永久抑制其目标。