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Towards practical sample preparation in point-of-care testing: user-friendly microfluidic devices.
Lab on a Chip ( IF 6.1 ) Pub Date : 2020-02-20 , DOI: 10.1039/d0lc00047g
Juhwan Park 1 , Dong Hyun Han , Je-Kyun Park
Affiliation  

Microfluidic technologies offer a number of advantages for sample preparation in point-of-care testing (POCT), but the requirement for complicated external pumping systems limits their wide use. To facilitate sample preparation in POCT, various methods have been developed to operate microfluidic devices without complicated external pumping systems. In this review, we introduce an overview of user-friendly microfluidic devices for practical sample preparation in POCT, including self- and hand-operated microfluidic devices. Self-operated microfluidic devices exploit capillary force, vacuum-driven pressure, or gas-generating chemical reactions to apply pressure into microchannels, and hand-operated microfluidic devices utilize human power sources using simple equipment, including a syringe, pipette, or simply by using finger actuation. Furthermore, this review provides future perspectives to realize user-friendly integrated microfluidic circuits for wider applications with the integration of simple microfluidic valves.

中文翻译:

在现场测试中实现实用的样品制备:用户友好的微流控设备。

微流体技术为即时检验(POCT)中的样品制备提供了许多优势,但是对复杂的外部泵送系统的要求限制了它们的广泛使用。为了促进POCT中的样品制备,已开发出多种方法来操作微流体设备而无需复杂的外部泵系统。在这篇综述中,我们介绍了用于POCT中实际样品制备的用户友好型微流体设备的概述,包括自操作和手动操作的微流体设备。自行操作的微流体设备利用毛细作用力,真空驱动的压力或产生气体的化学反应将压力施加到微通道中,而手动操作的微流体设备利用简单的设备(包括注射器,移液器)或通过简单地使用来利用人力资源手指驱动。此外,
更新日期:2020-02-20
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