In patients with fibrotic interstitial lung disease (ILD), hypoxaemia on exertion is frequent, and contributes to exercise intolerance, exertional dyspnoea and reduced quality of life [1–3]. Clinically significant exertional hypoxaemia is typically defined as a drop in transcutaneous arterial oxygen saturation (SpO2) to ≤88% on a 6-min walk test (6MWT) [4], and is associated with reduced survival in ILD patients [5]. In patients with interstitial lung disease, exertional hypoxaemia has quality of life and prognostic implications. A simple “DeOX” score predictive of exertional oxygen desaturation (SpO2 ≤88% on 6MWT) is proposed, using SpO2 at rest and DLCO. http://bit.ly/36ytigE

中文翻译：

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纤维化间质性肺病患者劳力性氧饱和度下降的生理预测因素

在纤维化间质性肺病 (ILD) 患者中，劳力性低氧血症很常见，会导致运动不耐受、劳力性呼吸困难和生活质量下降 [1-3]。临床上显着的劳力性低氧血症通常定义为经皮动脉血氧饱和度 (SpO2) 在 6 分钟步行试验 (6MWT) 中降至 ≤ 88% [4]，并且与 ILD 患者的生存率降低有关 [5]。在间质性肺病患者中，劳力性低氧血症对生活质量和预后有影响。提出了一个简单的“DeOX”评分来预测劳力性氧饱和度下降（SpO2 ≤ 88%，6MWT），使用静止时的 SpO2 和 DLCO。http://bit.ly/36ytigE