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Linking m6 A to Wnt signaling.
EMBO Reports ( IF 7.7 ) Pub Date : 2020-02-20 , DOI: 10.15252/embr.202050097
Xiao-Min Liu 1 , Shu-Bing Qian 2
Affiliation  

N6 -methyladenosine (m6 A) has emerged as a crucial molecular code to influence pluripotency and differentiation of diverse stem cells. A study in this issue now shows that, in intestinal stem cells, the m6 A reader protein YTHDF1 directs translational control of stemness in both m6 A- and Wnt-dependent manner [1].

中文翻译:

将m6 A链接到Wnt信令。

N6-甲基腺苷(m6 A)已成为影响多种干细胞多能性和分化的关键分子密码。现在,对此问题的研究表明,在肠道干细胞中,m6A阅读器蛋白YTHDF1以m6A依赖和Wnt依赖性方式指导干性的翻译控制[1]。
更新日期:2020-02-20
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