In 2010–11, evidence from clinical trials showed that pre-exposure prophylaxis (PrEP) was effective and safe for HIV prevention.^,  In high-income countries, where the epidemic is mainly concentrated among men who have sex with men, PrEP uptake initially grew slowly, then expanded in the second half of the decade as PrEP became more normalised through prevention guidelines, public health promotion, community conversations, and mass advertising. In countries and cities where PrEP has been delivered at scale in tandem with HIV testing, antiretroviral treatment, and other prevention strategies, new HIV infections in the past several years have declined substantially for the first time in at least a decade.^, 

中文翻译：

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来自SEARCH的PrEP课程在东非进行研究。

在2010-11年度，来自临床试验的证据表明，暴露前预防（PrEP）对于HIV预防是有效且安全的。^， 在流行主要集中在与男性发生性关系的男性的高收入国家中，PrEP的吸收起初缓慢增长，然后在十年的下半年随着预防性准则，公共卫生促进，社区的正常化而逐渐扩大对话和大量广告。在已经结合HIV检测，抗逆转录病毒治疗和其他预防策略大规模提供PrEP的国家和城市中，过去几年中，至少在十年中首次出现艾滋病新发感染率大幅下降的情况。^，