The Article by Mary E Crocker and colleagues in the Lancet Global Health taps into important scientific trends of improving the robustness of research and choosing the appropriate cutoffs for clinical diagnoses. Crocker and many global colleagues from the Home Air Pollution Improvement Network (HAPIN) write about the current WHO guidelines for diagnosing pneumonia in infants aged 0–23 months. They argue that WHO should acknowledge respiratory adaptation to high-altitude hypoxia by raising the threshold for respiratory rate (RR) and lowering that for oxygen saturation of haemoglobin (SpO₂) according to altitude. In the study, nearly 1600 infants represented four different altitude ranges from Guatemala, India, Rwanda, and Peru.

中文翻译：

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对高海拔婴儿进行深入研究。

《柳叶刀》全球健康杂志的Mary E Crocker及其同事撰写的文章探讨了重要的科学趋势，这些趋势提高了研究的稳定性并为临床诊断选择了适当的临界值。Crocker和来自家庭空气污染改善网络（HAPIN）的许多全球同事撰写了有关WHO诊断0-23个月大婴儿肺炎的现行指南。他们认为，WHO应根据海拔高度提高呼吸频率（RR）阈值和降低血红蛋白的氧饱和度（SpO ₂）阈值，从而承认呼吸系统适应于高原低氧。在这项研究中，来自危地马拉，印度，卢旺达和秘鲁的近1600名婴儿代表了四个不同的海拔范围。