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Repurposing fallen leaves to bio-based reaction medium for hydration, hydroxylation, carbon-carbon and carbon-nitrogen bond formation reactions
Sustainable Chemistry and Pharmacy ( IF 5.5 ) Pub Date : 2020-02-14 , DOI: 10.1016/j.scp.2020.100225
Sameeran Kumar Das , Khairujjaman Laskar , Dipika Konwar , Aniket Sahoo , Binoy K. Saikia , Utpal Bora

A green reaction medium has been developed from the Water Extract of Teak leaf (Tectona grandis) ash (WET). The alkaline nature of the WET was successfully applied towards hydration of nitriles, conversion of arylboronic acids to phenols with 30% aqueous H2O2, Knoevenagel condensation for benzylidenemalononitrile derivatives formation and Chan-Lam reaction of arylboronic acids with imidazole derivatives. In current protocols dual role of WET as reaction medium as well as base has been explored. A wide range of substrates with varying electronic natures is compatible under these WET mediated reaction conditions with excellent yields.



中文翻译:

将落叶重新用于生物基反应介质中以进行水合,羟基化,碳-碳和碳-氮键形成反应

从柚木叶(水蜜桃)灰(WET)的水提取物中开发了一种绿色反应介质。WET的碱性已成功应用于腈的水合,芳基硼酸与30%H 2 O 2水溶液的转化,苯甲基丙二腈衍生物形成的Knoevenagel缩合以及芳基硼酸与咪唑衍生物的Chan-Lam反应中。在当前方案中,已经探索了WET作为反应介质和碱的双重作用。在这些WET介导的反应条件下,具有各种电子性质的多种底物均具有优异的收率。

更新日期:2020-02-14
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