Metal–organic frameworks (MOFs) have recently been demonstrated to be excellent platforms for biomedical applications. On account of their porous nature and modular structure, MOFs have served as bioactive-compound carriers, cell-imaging materials, and therapeutic agents. MOF cavities allow the encapsulation of a variety of guest molecules, facilitating controllable drug release and optical imaging. The metal components of MOFs make them suitable for magnetic resonance imaging (MRI) and computed tomography (CT). Additionally, MOF-embedded therapeutic agents have demonstrated promise in photodynamic and photothermal therapies. In this review, we describe several advanced examples that utilize MOFs in these cutting-edge applications. Investigation of the relationship between their structure and designated application will enable future, informed exploration of MOFs for biomedical applications.

金属有机框架（MOF）最近已被证明是生物医学应用的绝佳平台。由于其多孔性和模块化结构，MOF可用作生物活性化合物载体，细胞成像材料和治疗剂。MOF腔允许封装各种来宾分子，从而促进可控的药物释放和光学成像。MOF的金属成分使其适用于磁共振成像（MRI）和计算机断层扫描（CT）。此外，嵌入MOF的治疗剂已在光动力和光热疗法中显示出希望。在这篇综述中，我们描述了几个在这些尖端应用中利用MOF的高级示例。研究它们的结构与指定应用之间的关系将为将来，