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The new koninginins T-U from Phomopsis stipata, an endophytic fungus isolated from Styrax camporum Pohl
Phytochemistry Letters ( IF 1.3 ) Pub Date : 2020-02-07 , DOI: 10.1016/j.phytol.2020.01.019
Carolina R. Biasetto , Andressa Somensi , Renata Sordi , Vanessa M. Chapla , Samad N. Ebrahimi , Geraldo H. Silva , Helder L. Teles , Vanderlan da S. Bolzani , Maria Cláudia M. Young , Ludwig H. Pfenning , Angela R. Araujo

Two new polyketides, named koninginin T (1) and U (2), were isolated from Phomopsis stipata - an endophytic fungus isolated from Styrax camporum Pohl. The structures of polyketides 1 and 2 were defined through the analysis of spectroscopic data. Antifungal and acetylcholinesterase inhibitory activities of these compounds were evaluated using TLC bioautographic assays. Compounds 1 and 2 displayed moderate antifungal activity and compound 1 showed acetylcholinesterase inhibitory activity.



中文翻译:

从新koninginins TU拟茎点stipata,一个内生真菌分离自苏合香camporum波尔

两个新的聚酮化合物,命名为koninginin T(1)和U(2)中,从分离拟茎点霉stipata的内生真菌分离自-苏合香camporum波尔。聚酮化合物12的结构是通过光谱数据分析确定的。这些化合物的抗真菌和乙酰胆碱酯酶抑制活性使用TLC生物自显影测定法进行评估。化合物12显示中等的抗真菌活性,化合物1显示乙酰胆碱酯酶的抑制活性。

更新日期:2020-02-20
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