New phenylethanoid, glucooleoacteoside (2), along with 18 known compounds were isolated from the aqueous extract of Osmanthus fragrans. The structure of new compound was elucidated on the base of IR, HR-ESI-MS, 1D NMR, 2D NMR and DEPT analysis. Bioactivity investigation into human dermal fibroblasts (HDF) proliferation, type I collagen expression, and MMP-1 expression were examined with six phenylethanoids. We found that compounds 1, 3, 4, 7, and 9 showed moderate bioactivities. In conclusion, we demonstrated that the aqueous extract of flower of O. fragrans contained phenylethanoid-rich constituents which revealed bioactivities at the cellular level of HDFs.

从桂花的水提物中分离出新的苯乙醇类，葡糖油苷（2）以及18种已知化合物。根据IR，HR-ESI-MS，1D NMR，2D NMR和DEPT分析，阐明了新化合物的结构。用六个苯基乙醛类化合物检查了人类皮肤成纤维细胞（HDF）增殖，I型胶原蛋白表达和MMP-1表达的生物活性。我们发现，化合物1，3，4，图7，和9显示出中等的生物活性。总之，我们证明了香茅花的水提取物 含有富含苯乙醛的成分，这些成分在高密度脂蛋白的细胞水平上具有生物活性。