Here I review vertebral fractures (VFs) as an emerging complication of acromegaly through a pathway of key questions in order to help clinicians manage the disease. Peculiarities of acromegalic osteopathy are that VFs are common but not explained by low bone mineral density (BMD) being related to disease duration and activity, and occurring even after remission.

中文翻译：

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肢端肥大症和椎骨骨折：事实和问题

在这里，我通过一系列关键问题回顾了作为肢端肥大症新出现的并发症的椎骨骨折 (VF)，以帮助临床医生管理这种疾病。肢端肥大症骨病的特点是 VF 很常见，但不能用与疾病持续时间和活动相关的低骨密度 (BMD) 来解释，甚至在缓解后也会发生。