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Issues important to the design of stroke recovery trials.
The Lancet Neurology ( IF 46.5 ) Pub Date : 2020-03-01 , DOI: 10.1016/s1474-4422(20)30030-2
Steven C Cramer 1
Affiliation  

Stroke recovery trials aim to improve outcomes by promoting repair in surviving neural systems, by contrast with acute reperfusion trials, which aim to salvage threatened tissue by targeting clots and arteries. Several drugs, biologicals, devices, and behavioural training paradigms have shown promise in preclinical studies targeting repair.

中文翻译:

对中风恢复试验设计很重要的问题。

与急性再灌注试验相反,中风恢复试验旨在通过促进存活神经系统的修复来改善结局,而急性再灌注试验旨在通过靶向血栓和动脉来挽救受威胁的组织。在针对修复的临床前研究中,几种药物,生物制品,设备和行为训练范例已显示出希望。
更新日期:2020-02-19
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