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Correction to Discovery of N-(4-[18F]Fluoro-5-methylpyridin-2-yl)isoquinolin-6-amine (JNJ-64326067), a New Promising Tau Positron Emission Tomography Imaging Tracer.
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 2020-02-18 , DOI: 10.1021/acs.jmedchem.0c00140
Frederik J. R. Rombouts , Lieven Declercq , José-Ignacio Andrés , Astrid Bottelbergs , Lu Chen , Laura Iturrino , Joseph E. Leenaerts , Jonas Mariën , Fengbin Song , Cindy Wintmolders , Stijn Wuyts , Chunfang A. Xia , Paula te Riele , Guy Bormans , Rik Vandenberghe , Hartmuth Kolb , Diederik Moechars

Page 2979. The caption of Figure 1 should be the following: Figure 1. Autoradiography images of adjacent 10 μm thick, tau, and Aβ pathology-rich (A, B) or Aβ pathology-only-rich (E, F) post-mortem human AD brain slices after incubation with 10 nM [3H]9 (A, E) or 3 nM [3H]AV-45 (B, F). The presence of tau and Aβ pathology was confirmed by AT8 (D, H) and 4G8 (C, G) immunostaining. For the tau and Aβ pathology-rich slice, this was done on a nonadjacent section from the same patient (C, D, black bar is 10 mm). For the Aβ pathology-only-rich slice, this was done on an adjacent section (G,H, black bar is 2 mm). This article has not yet been cited by other publications.

中文翻译:

对发现新的有希望的Tau正电子发射断层成像示踪剂N-(4- [18F]氟-5-甲基吡啶-2-基)异喹啉-6-胺(JNJ-64326067)的发现进行校正。

Page2979。图1的标题如下:图1.放射后的相邻10μm厚,tau和Aβ病理丰富(A,B)或仅Aβ病理丰富(E,F)的放射自显影图像。用10 nM [ 3 H] 9(A,E)或3 nM [ 3 H] AV-45(B,F)孵育后的尸体人类AD脑切片。通过AT8(D,H)和4G8(C,G)免疫染色证实了tau和Aβ病理的存在。对于tau和Aβ病理丰富的切片,该切片是在同一位患者的不相邻切片上完成的(C,D,黑条为10 mm)。对于仅包含Aβ病理的切片,该切片在相邻切片上完成(G,H,黑条为2 mm)。本文尚未被其他出版物引用。
更新日期:2020-02-19
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