Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide,Organic Process Research & Development

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Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide
Organic Process Research & Development ( IF 3.1 ) Pub Date : 2020-02-28 , DOI: 10.1021/acs.oprd.0c00005
David L. Hughes ₁

Affiliation

This article reviews the synthetic routes and final crystalline forms of the recently approved antiandrogen drugs enzalutamide, apalutamide, and darolutamide, used for the treatment of prostate cancer. The patent literature was the primary source of information.

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