Peptide-targeting probes tagged with optical imaging and PET reporters may find applications in innovative diagnostic procedures and image-guided surgeries. The reported synthesis procedure is of general applicability to obtain dual imaging probes using fully unprotected moieties with a selective and rapid chemistry based on native chemical ligation.

中文翻译：

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一种基于天然化学连接方法的双模态肽成像探针合成的创新方法。

标记有光学成像和PET报道分子的靶向肽的探针可能会在创新的诊断程序和图像引导的手术中找到应用。所报道的合成方法一般适用于使用完全未保护的部分并基于天然化学连接的选择性和快速化学方法获得双重成像探针。