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Ruthenium‐Catalyzed meta‐CAr–H Bond Difluoroalkylation of 2‐Phenoxypyridines
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-03-17 , DOI: 10.1002/ejoc.201901883
Chunqi Jia 1 , Shichong Wang 2 , Xulu Lv 2 , Gang Li 2 , Lei Zhong 2 , Lei Zou 2 , Xiuling Cui 1
Affiliation  

A ruthenium‐catalyzed meta‐selective CAr–H bond difluoroalkylation of 2‐phenoxypyridine using 2‐bromo‐2,2‐difluoroacetate has been developed, which provide a new method to synthesize 2‐(meta‐difluoroalkylphenoxy)pyridine derivatives, which are present in many pharmaceuticals and other functional compounds.
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中文翻译:

钌催化的2-苯氧基吡啶的间CAr-H键二氟烷基化

有人开发了使用2-溴-2,2-二氟乙酸的钌催化的2-苯氧基吡啶的选择性C Ar -H键二氟烷基化反应,为合成2-(二氟烷基苯氧基)吡啶衍生物提供了一种新方法。存在于许多药物和其他功能性化合物中。
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更新日期:2020-03-19
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