In this Letter, we present, to the best of our knowledge, a novel illumination modulation method for reflective and fluorescent separation by using only one spectral image. Specifically, we present an optical system using off-the-shelf devices to generate high frequency illumination, which is desirable in reflective-fluorescent separation tasks. In addition, we employ the total variation regularization scheme to account for spectral-spatial correlation, which makes our method robust to noise. Experiments on both simulated and real data verify the effectiveness and practicality of our method.

中文翻译：

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用于反射和荧光分离的照明调制。

在本信中，我们将尽我们所能介绍一种仅通过使用一个光谱图像进行反射和荧光分离的新型照明调制方法。具体而言，我们介绍了一种使用现成的设备来生成高频照明的光学系统，这在反射荧光分离任务中是理想的。此外，我们采用了总变化正则化方案来解决频谱空间相关性，这使我们的方法对噪声具有鲁棒性。在模拟和真实数据上的实验证明了我们方法的有效性和实用性。