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Mapping cell phenotypes in breast cancer
Nature Cancer ( IF 23.5 ) Pub Date : 2020-02-17 , DOI: 10.1038/s43018-020-0031-9 Leeat Keren 1 , Michael Angelo 1
Nature Cancer ( IF 23.5 ) Pub Date : 2020-02-17 , DOI: 10.1038/s43018-020-0031-9 Leeat Keren 1 , Michael Angelo 1
Affiliation
Tumor heterogeneity remains an obstacle to effective clinical management of breast cancer. Two new studies use high-dimensional imaging of single-cell protein expression in situ in clinical samples to link genomic alterations to multi-cellular features of the tumor microenvironment and reveal breast-cancer phenotypes associated with clinical outcome.
中文翻译:
绘制乳腺癌细胞表型
肿瘤异质性仍然是有效临床治疗乳腺癌的障碍。两项新研究使用临床样本中单细胞蛋白原位表达的高维成像,将基因组改变与肿瘤微环境的多细胞特征联系起来,并揭示与临床结果相关的乳腺癌表型。
更新日期:2020-02-17
中文翻译:
绘制乳腺癌细胞表型
肿瘤异质性仍然是有效临床治疗乳腺癌的障碍。两项新研究使用临床样本中单细胞蛋白原位表达的高维成像,将基因组改变与肿瘤微环境的多细胞特征联系起来,并揭示与临床结果相关的乳腺癌表型。