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B is for ‘Big Mac’: GCs crave a high-fat diet
Nature Immunology ( IF 27.7 ) Pub Date : 2020-02-17 , DOI: 10.1038/s41590-020-0614-8 Juhee Pae , Gabriel D. Victora
Nature Immunology ( IF 27.7 ) Pub Date : 2020-02-17 , DOI: 10.1038/s41590-020-0614-8 Juhee Pae , Gabriel D. Victora
Highly proliferative cells have classically been thought to rely on anaerobic glycolysis for fuel. Weisel et al. show that germinal center B cells break this rule, as they primarily utilize fatty acid oxidation to meet their metabolic demands.
中文翻译:
B代表“巨无霸”:GC渴望高脂饮食
传统上认为高度增殖性细胞依赖于厌氧糖酵解作为燃料。Weisel等。表明生发中心B细胞违反了这一规则,因为它们主要利用脂肪酸氧化来满足其代谢需求。
更新日期:2020-02-17
中文翻译:
B代表“巨无霸”:GC渴望高脂饮食
传统上认为高度增殖性细胞依赖于厌氧糖酵解作为燃料。Weisel等。表明生发中心B细胞违反了这一规则,因为它们主要利用脂肪酸氧化来满足其代谢需求。