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Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI
Magnetic Resonance Materials in Physics Biology and Medicine ( IF 2.0 ) Pub Date : 2019-11-22 , DOI: 10.1007/s10334-019-00797-5
Ilona A. Dekkers , Anneloes de Boer , Kaniska Sharma , Eleanor F. Cox , Hildo J. Lamb , David L. Buckley , Octavia Bane , David M. Morris , Pottumarthi V. Prasad , Scott I. K. Semple , Keith A. Gillis , Paul Hockings , Charlotte Buchanan , Marcos Wolf , Christoffer Laustsen , Tim Leiner , Bryan Haddock , Johannes M. Hoogduin , Pim Pullens , Steven Sourbron , Susan Francis

To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and T2 mapping participated in a consensus project, which was initiated by the European Cooperation in Science and Technology Action PARENCHIMA CA16103. Consensus recommendations were formulated using a two-step modified Delphi method. The first survey consisted of 56 items on T1 mapping, of which 4 reached the pre-defined consensus threshold of 75% or higher. The second survey was expanded to include both T1 and T2 mapping, and consisted of 54 items of which 32 reached consensus. Recommendations based were formulated on hardware, patient preparation, acquisition, analysis and reporting. Consensus-based technical recommendations for renal T1 and T2 mapping were formulated. However, there was considerable lack of consensus for renal T1 and particularly renal T2 mapping, to some extent surprising considering the long history of relaxometry in MRI, highlighting key knowledge gaps that require further work. This paper should be regarded as a first step in a long-term evidence-based iterative process towards ever increasing harmonization of scan protocols across sites, to ultimately facilitate clinical implementation.



中文翻译:

基于共识的肾脏T1和T2映射MRI技术翻译的技术建议

为获取有关肾纵(T1)和横(T2)弛豫时间图的采集和后处理的技术建议。由欧洲T1和T2映射领域的18位专家组成的多学科小组参加了一项共识项目,该项目由欧洲科学技术合作组织PARENCHIMA CA16103启动。使用两步改进的Delphi方法制定了共识建议。第一次调查由T1映射上的56个项目组成,其中4个达到预定义共识阈值75%或更高。第二次调查已扩展到包括T1和T2映射,并且包括54个项目,其中32个达成了共识。基于硬件,患者准备,获取,分析和报告制定了建议。制定了针对肾脏T1和T2定位的基于共识的技术建议。但是,对于肾脏T1尤其是肾脏T2映射,仍然缺乏共识,考虑到MRI弛豫法的悠久历史,这在某种程度上令人惊讶,突出了需要进一步开展工作的关键知识差距。本文应被视为长期循证迭代过程的第一步,旨在不断提高跨站点的扫描协议的协调性,从而最终促进临床实施。

更新日期:2019-11-22
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