The National Heart, Lung, and Blood Institute convened a multidisciplinary working group of hypertension researchers on December 6 to 7, 2018, in Bethesda, MD, to share current scientific knowledge in hypertension and to identify barriers to translation of basic into clinical science/trials and implementation of clinical science into clinical care of patients with hypertension. The goals of the working group were (1) to provide an overview of recent discoveries that may be ready for testing in preclinical and clinical studies; (2) to identify gaps in knowledge that impede translation; (3) to highlight the most promising scientific areas in which to pursue translation; (4) to identify key challenges and barriers for moving basic science discoveries into translation, clinical studies, and trials; and (5) to identify roadblocks for effective dissemination and implementation of basic and clinical science in real-world settings. The working group addressed issues that were responsive to many of the objectives of the National Heart, Lung, and Blood Institute Strategic Vision. The working group identified major barriers and opportunities for translating research to improved control of hypertension. This review summarizes the discussion and recommendations of the working group.

中文翻译：

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国家心肺血液研究所高血压工作组报告


国家心肺血液研究所于 2018 年 12 月 6 日至 7 日在马里兰州贝塞斯达召集了高血压研究人员多学科工作组，分享当前高血压的科学知识，并确定将基础知识转化为临床科学/试验的障碍将临床科学应用到高血压患者的临床护理中。该工作组的目标是（1）概述可能准备在临床前和临床研究中进行测试的最新发现； (2) 找出阻碍翻译的知识差距； (3) 突出最有前途的翻译科学领域； (4) 确定将基础科学发现转化为转化、临床研究和试验的主要挑战和障碍； (5) 找出在现实环境中有效传播和实施基础科学和临床科学的障碍。该工作组解决了响应国家心肺血液研究所战略愿景许多目标的问题。该工作组确定了将研究转化为改善高血压控制的主要障碍和机遇。本次审查总结了工作组的讨论和建议。