In Reply We thank Singh et al for their comments on our article¹ demonstrating the benefits of specialist neurology and comprehensive epilepsy care on mortality in patients with epilepsy. We agree that evidence-based care should be driven by data. In a global environment of accelerating health care costs,² the same methods should be used to demonstrate value for money. However, it may be unsurprising that bespoke care improves outcomes; particularly pertinent for countries offering universal health coverage, the unequivocal demonstration of benefit is an indispensable prerequisite for advocates of the judicious use of finite health care resources. Our study clearly demonstrates said value as referral to a comprehensive epilepsy program (hazard ratio, 0.49; 95% CI, 0.38-0.62) robustly reduces premature mortality,¹ a problem that contributes to epilepsy existing as the third most common neurological cause of years lived with disability in the world.³

在答复中，我们感谢Singh等人对我们的文章¹的评论，该文章证明了专科神经病学和综合癫痫治疗对癫痫患者死亡率的益处。我们同意，循证护理应以数据为驱动力。在全球医疗费用不断上涨的环境中，²应该使用相同的方法来证明物有所值。但是，量身定制的护理可以改善预后，这并不奇怪。特别是对于提供全民医疗保险的国家而言，明确表明受益是倡导明智地使用有限医疗资源的必要条件。我们的研究清楚地表明，将其作为综合性癫痫治疗计划的参考价值（危险比，0.49； 95％CI，0.38-0.62）可有效降低过早死亡，¹这是导致癫痫症的一个问题，已成为多年以来第三大最常见的神经系统病因世界上有残疾的人 ³