Although rare in occurrence, adverse events such as delayed bleeding and buried stent syndrome have been reported after lumen-apposing metal stents (LAMS) placement in patients undergoing endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFCs). In a prospective study, we observed delayed adverse events in 6.4% of 188 patients which occurred when the PFCs were 7 cm or smaller in size and the removal of LAMS was delayed beyond 4 weeks. LAMS are being increasingly preferred over double pigtail plastic stents for patients undergoing EUS-guided PFC drainage because their deployment is technically easy and the wide lumen facilitates quick drainage of cyst contents. However, delayed adverse events such as bleeding and buried stent syndrome have been reported after LAMS placement.1–3 In this study, we attempted to identify predictors of adverse events by examining data that were collected prospectively in all patients undergoing EUS-guided PFC drainage using LAMS. By institutional protocol, after LAMS placement, the endoprostheses were removed at outpatient follow-up in 3–4 weeks and all patients were contacted by telephone call to obtain follow-up at 6 months. The data collected included 292 demographic, laboratory, radiological, technical, clinical and treatment outcome variables, with a minimum follow-up duration of 6 months (NCT02422095). Patient details, PFC characteristics, disease severity and clinical outcomes were summarised as means with SD and medians with IQR for continuous variables and as frequencies and proportions for categorical variables. In order to identify the factors associated with …

中文翻译：

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腔内金属支架置入引流胰腺积液：不良事件的预测因素

尽管很少发生，但在接受内窥镜超声 (EUS) 引导的胰腺积液 (PFC) 引流术的患者中放置管腔对置金属支架 (LAMS) 后，已经报告了延迟出血和埋藏支架综合征等不良事件。在一项前瞻性研究中，我们观察到 188 名患者中有 6.4% 的延迟不良事件发生在 PFC 大小为 7 厘米或更小且 LAMS 的移除延迟超过 4 周时发生。对于接受 EUS 引导的 PFC 引流术的患者，LAMS 越来越比双尾纤塑料支架更受青睐，因为它们的部署在技术上很容易，而且宽管腔有利于囊肿内容物的快速引流。然而，在 LAMS 置入后，已经报告了诸如出血和埋藏支架综合征等延迟性不良事件。 1-3 在本研究中，我们试图通过检查在所有使用 LAMS 进行 EUS 引导 PFC 引流的患者中前瞻性收集的数据来确定不良事件的预测因素。根据机构协议，在 LAMS 放置后，在 3-4 周的门诊随访时取出内置假体，并通过电话联系所有患者，以便在 6 个月时进行随访。收集的数据包括 292 个人口统计学、实验室、放射学、技术、临床和治疗结果变量，最短随访时间为 6 个月 (NCT02422095)。患者详细信息、PFC 特征、疾病严重程度和临床结果被总结为连续变量的均值和 IQR，以及分类变量的频率和比例。为了确定与……相关的因素 LAMS 置入后，在门诊随访 3-4 周时取出内置假体，并在 6 个月时通过电话联系所有患者以获得随访。收集的数据包括 292 个人口统计学、实验室、放射学、技术、临床和治疗结果变量，最短随访时间为 6 个月 (NCT02422095)。患者详细信息、PFC 特征、疾病严重程度和临床结果被总结为连续变量的均值和 IQR，以及分类变量的频率和比例。为了确定与……相关的因素 LAMS 置入后，在门诊随访 3-4 周时取出内置假体，并在 6 个月时通过电话联系所有患者以获得随访。收集的数据包括 292 个人口统计学、实验室、放射学、技术、临床和治疗结果变量，最短随访时间为 6 个月 (NCT02422095)。患者详细信息、PFC 特征、疾病严重程度和临床结果被总结为连续变量的均值和 IQR，以及分类变量的频率和比例。为了确定与……相关的因素 放射学、技术、临床和治疗结果变量，最短随访时间为 6 个月 (NCT02422095)。患者详细信息、PFC 特征、疾病严重程度和临床结果被总结为连续变量的均值和 IQR，以及分类变量的频率和比例。为了确定与……相关的因素 放射学、技术、临床和治疗结果变量，最短随访时间为 6 个月 (NCT02422095)。患者详细信息、PFC 特征、疾病严重程度和临床结果被总结为连续变量的均值和 IQR，以及分类变量的频率和比例。为了确定与……相关的因素