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Recent advances in fluorescence sensors based on DNA-MOF hybrids.
Luminescence ( IF 3.2 ) Pub Date : 2020-02-16 , DOI: 10.1002/bio.3790
Fen Wu 1 , Jianhan Ye 1 , Yulu Cao 1 , Ziyuan Wang 1 , Tingting Miao 1 , Qian Shi 1
Affiliation  

In this review, the recent advances in the development of fluorescence sensors based on DNA and metal-organic framework hybrids have been reported for nucleic acid, metal ion and amino acid detection. The main detection mechanism depends on different adsorption capacities of MOFs towards different DNA structures (single-stranded DNA, double-stranded DNA), and consequently the fluorescence intensity of probe DNA is changed. These results might open up a way to study their potential application in material science and clinical diagnosis of some related diseases.

中文翻译:

基于DNA-MOF杂交体的荧光传感器的最新进展。

在这篇综述中,已经报道了基于DNA和金属-有机框架杂交体的荧光传感器的最新进展,用于核酸,金属离子和氨基酸的检测。主要的检测机制取决于MOF对不同DNA结构(单链DNA,双链DNA)的不同吸附能力,因此探针DNA的荧光强度发生了变化。这些结果可能为研究其在材料科学和某些相关疾病的临床诊断中的潜在应用开辟道路。
更新日期:2020-02-16
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