BACKGROUND To experimentally compare the optical performance of two different Extended-Depth-of-Focus (EDOF) intraocular lenses (IOLs) using a standardized optical bench set-up. METHODS In this experimental study, following IOLs were assessed: the TECNIS® Symfony ZXR00 (Johnson&Johnson, Santa Ana, USA) and the AT LARA 829MP (Carl Zeiss Meditec, Jena, Germany) IOLs. The through-focus modulation transfer function (MTF) values were measured at a spatial frequency of 50 lp/mm and at aperture sizes of 2, 3, and 4.5 mm. Each IOL was measured while centered using ISO 11979-2 Model 1 (aberration-free) and Model 2 (+ 0.28 μm spherical aberration) corneas. United States Air Force (USAF) target images were also recorded for a qualitative evaluation. RESULTS At 2 mm pupil with ISO1 cornea, the primary and secondary foci of both IOLs appeared to merge, providing an elongated depth of focus. At 3 and 4.5 mm pupil sizes, the through-focus MTF curves of both IOLs showed a bifocal-like V-pattern. While the Symfony IOL showed an overall superior MTF values when measured with the ISO2 cornea, the opposite propensity could be observed with the AT LARA IOL. This optical behavior could be qualitatively confirmed by the USAF target images. CONCLUSIONS Although the two EDOF IOLs share similarities in their optical properties, the main difference lies in their optical design and performance with respect to spherical aberration. Such characteristics should be taken into account during IOL and patient selection.

中文翻译：

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实验室评估的两个扩展焦深人工晶体的光学特性。

背景技术为了实验上使用标准的光学平台装置比较两个不同的焦深（EDOF）人工晶状体（IOL）的光学性能。方法在本实验研究中，对以下IOL进行了评估：TECNIS®Symfony ZXR00（Johnson＆Johnson，美国圣安娜）和AT LARA 829MP（Carl Zeiss Meditec，德国耶拿）IOL。在50 lp / mm的空间频率和2、3和4.5 mm的孔径下测量通过焦点的调制传递函数（MTF）值。使用ISO 11979-2模型1（无像差）和模型2（+ 0.28μm球差）角膜对中时，测量每个IOL。还记录了美国空军（USAF）的目标图像，以进行定性评估。结果在瞳孔为2 mm且具有ISO1角膜的情况下，两个IOL的原发灶和继发灶似乎合并了，提供长焦距。在3mm和4.5mm的瞳孔尺寸下，两个IOL的全焦点MTF曲线显示出双焦点状的V型。当使用ISO2角膜测量时，Symfony IOL显示出总体优越的MTF值，而使用AT LARA IOL可以观察到相反的倾向。这种光学行为可以由USAF目标图像定性地确认。结论尽管两个EDOF IOL的光学特性相似，但主要区别在于其光学设计和球差方面的性能。在IOL和患者选择期间应考虑这些特征。当用ISO2角膜测量时，Symfony IOL显示出总体上优越的MTF值，而使用AT LARA IOL可以观察到相反的倾向。这种光学行为可以由USAF目标图像定性地确认。结论尽管两个EDOF IOL的光学特性相似，但主要区别在于其光学设计和球差方面的性能。在IOL和患者选择期间应考虑这些特征。当使用ISO2角膜测量时，Symfony IOL显示出总体优越的MTF值，而使用AT LARA IOL可以观察到相反的倾向。这种光学行为可以由USAF目标图像定性地确认。结论尽管两个EDOF IOL的光学特性相似，但主要区别在于其光学设计和球差方面的性能。在IOL和患者选择期间应考虑这些特征。主要区别在于它们在球差方面的光学设计和性能。在IOL和患者选择期间应考虑这些特征。主要区别在于它们在球差方面的光学设计和性能。在IOL和患者选择期间应考虑这些特征。