Organosulfur compounds are important moieties found in several medicinal drugs used in the therapy of arthritis, cancer, depression, diabetes or immune deficiency syndrome. Furthermore, organosulfur compounds are intermediates in many organic reactions with a key role as ligands or chiral auxiliaries. Due to their importance in various areas as pharmaceutical chemistry, synthetic organic chemistry, as well as materials science, the development of new and more sustainable synthetic protocols to provide access to different organosulfur compounds, has a high impact on the broader chemistry community. Many interesting transformations of organosulfur compounds involve an oxidation reaction to access to organosulfur derivatives such as disulfide, sulfinyl or sulfones. Organosulfur oxidation is typically carried out using different oxidant agents such as peroxides, peracids or using atmosphere oxygen under photocatalysis. Despite the numerous procedures reported in the academia, the developments of oxidation of organosulfur compounds with an industrial interest has been limited in regard to the scaling-up, sustainable and safer process. In this context, the use of continuous-flow technology has allowed overcome the disadvantaged of batch approach and is a bridge to connect the academia with the industry. The aim of this review is to highlight the importance of applying flow chemistry methodology as a greener and scalable process in the oxidation of organosulfur compounds. Additionally, a critical view of the different developed methodologies and a future view in the employ of organosulfur oxidation are discussed.

有机硫化合物是在治疗关节炎，癌症，抑郁症，糖尿病或免疫缺陷综合症的几种药物中发现的重要部分。此外，有机硫化合物是许多有机反应的中间体，具有作为配体或手性助剂的关键作用。由于它们在药物化学，合成有机化学以及材料科学等各个领域的重要性，因此开发新的，更具可持续性的合成规程以提供获取不同有机硫化合物的途径，对更广泛的化学界产生了重大影响。有机硫化合物的许多有趣的转变都涉及氧化反应，以得到有机硫衍生物，例如二硫化物，亚磺酰基或砜。有机硫的氧化通常使用不同的氧化剂（例如过氧化物，过酸）或在光催化下使用大气中的氧气进行。尽管学术界报道了许多程序，但是在扩大规模，可持续和更安全的过程方面，具有工业兴趣的有机硫化合物氧化的发展受到限制。在这种情况下，连续流技术的使用已经克服了分批处理方法的缺点，并且是将学术界与工业界联系起来的桥梁。这篇综述的目的是强调在有机硫化合物的氧化过程中应用流化学方法作为一种绿色且可扩展的方法的重要性。另外，