A growing body of evidence has indicated that individuals with autism spectrum disorder (ASD) exhibit abnormal reactions to sensory stimuli and impaired face processing. Although behavioral studies have reported that individual differences in sensory processing patterns are correlated with performance in face processing tasks, the neural substrates underlying the association between sensory processing patterns and face processing remain unknown. Using functional magnetic resonance imaging, the present study examined the relationships between sensory processing patterns assessed with the Adolescent/Adult Sensory Profile (AASP) and brain activity during a one‐back task with two types of stimuli (face or house pictures). We enrolled 18 Japanese adults with ASD and 19 age‐ and IQ‐matched controls. Sensation Avoiding scores, which were assessed using the AASP, were positively correlated with right fusiform activity during the presentation of pictures of faces in the ASD group, but not in the control group. This suggests that abnormal sensory processing patterns in ASD are associated with abnormal face‐related brain activity, possibly resulting in impaired face processing. Autism Res 2020, 13: 741–750. © 2020 International Society for Autism Research, Wiley Periodicals, Inc.

中文翻译：

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自闭症谱系障碍者在面部处理过程中的感觉处理模式和梭形活动。

越来越多的证据表明，患有自闭症谱系障碍（ASD）的人对感觉刺激表现出异常反应，面部表情受损。尽管行为研究报告说，感觉处理模式中的个体差异与面部处理任务的表现相关，但感觉处理模式与面部处理之间的关联所基于的神经基质仍然未知。本研究使用功能性磁共振成像检查了通过青少年/成人感觉概况（AASP）评估的感觉处理模式与在一次刺激任务中使用两种类型的刺激（面部或房屋图片）之间的大脑活动之间的关系。我们招募了18名患有ASD的日本成年人以及19名年龄和智商相匹配的对照组。避免感觉得分，使用AASP进行评估的结果与ASD组（而不是对照组）的面部图片呈现过程中的右梭形活动呈正相关。这表明ASD中异常的感觉处理模式与面部相关的大脑活动异常相关，可能导致面部处理受损。Autism Res 2020，13：741–750。©2020国际自闭症研究协会，Wiley Periodicals，Inc.。