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Regulation of integrin α6A by lactogenic hormones in rat pancreatic β-cells: Implications for the physiological adaptation to pregnancy.
Acta Physiologica ( IF 5.6 ) Pub Date : 2020-02-13 , DOI: 10.1111/apha.13454
Annette Møldrup 1 , Martin Nerup Lindberg 2 , Elisabeth D Galsgaard 1 , Ulrik Henriksen 3 , Louise T Dalgaard 4 , Jens Høiriis Nielsen 3
Affiliation  

During pregnancy, the maternal β‐cell mass is increased in order to adapt to the physiological changes in insulin demand. Lactogenic hormones stimulate rodent β‐cell attachment and proliferation in vitro. The aim of this study was to identify adhesion molecules involved in expansion of the β‐cell mass during pregnancy in the rat.

中文翻译:

促胰激素对大鼠胰岛β细胞中整联蛋白α6A的调节:对妊娠生理适应的意义。

在怀孕期间,孕妇的β细胞量会增加,以适应胰岛素需求的生理变化。促乳激素可在体外刺激啮齿动物的β细胞附着和增殖。这项研究的目的是鉴定在大鼠妊娠期间参与β细胞量膨胀的粘附分子。
更新日期:2020-02-13
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